Peptidomimetics

Group of reference and pioneering in Spain in peptidomimetics. Our research requires coordinated use of molecular modeling, synthetic methodologies in solution and solid-phase (peptides/small molecules) and biological evaluation. Experience in enzymatic inhibitors, mimetics of analgesic and antitumor peptides, and of neuropeptides. Focused currently in the identification of protein-protein modulators, key in tumor and neurodegenerative processes, on the modulation of different ion channels and associated proteins (for new analgesic, antitumor, cardiovascular and neuroprotective agents), and on fluorescent probes for biosensors. Constants of the group:collaboration with other groups, pharmaceutical companies (Antibióticos; NovoNordisk; PharmaMar; Givaudan; Alodia; Mediczen), and the multidisciplinary training of young researchers. Participation in COST actions (BM1301 y BM1406).