Bioinformatics and Functional Genomics

Dr. JAVIER DE LAS RIVAS (MSc, PhD, Investigador Científico CSIC, PI at the IMBCC). His group works on 2 main research areas: (i) Development and application of BIOINFORMATICS and COMPUTATIONAL BIOLOGY methods for "omics" data analysis, focusing on the integration of genomic, transcriptomic and proteomic data. All in the field of FUNCTIONAL GENOMICS for: gene expression profiling (pcRNAs and ncRNAs), identification of gene signatures and causal/driver genes, with special interest on "cancer studies" over human samples derived from clinical cohorts. This is done in close collaboration with medical groups, in particular with onco-hematologists of the University Hospital. (ii) Research on protein-protein interactions (PPIs), interactomes and protein networks, with application to the study of different complex diseases or pathological states. The research on this area also includes work on proteins sequence-structure analysis, proteins evolutionary traits and "in silico" protein design.