Pathogenomics

Our scientific approach is to study microbial pathogens in the context of their host and disease. To do this, we focus, but not exclusively, on the study of obligate intracellular bacteria with a wide host range such as tuberculosis and brucellosis. We will try to understand the basis of virulence in a given host, for a better understanding of the virulence of the pathogen. We employ a range of different omics where genomics is our main approach to study the evolution and molecular molecular epidemiology of the pathogen. But we also perform experimental infections to discover which genomic determinants are responsible.