Skip to main content
 
Tipo de expresión:
Doctorado: Propuesta de dirección de tesis doctoral/temática para solicitar ayuda predoctoral ("Hosting Offer o EoI")

Ámbito:
BIOLOGÍA SINTÉTICA Y DE SISTEMAS

Área:
Vida

Modalidad:
Ayudas para contratos predoctorales para la formación de doctores (antiguas FPI)

Referencia:
PIF2024

Centro o Instituto:
CENTRO NACIONAL DE BIOTECNOLOGIA

Palabras clave:
synthetic biology, systems biology, biocomputation, multicellular, bacteria

Documentos anexos:
666088.pdf

PIF2024 - Multicellular computing with engineered bacterial communities (PID2023-152470NB-I00)

By using bacterial conjugation as a messaging protocol, MULTI-SYNBIO aims to implement synthetic multicellular consortia with unprecedented computing capabilities. In contrast to quorum sensing (QS), the most-used messaging protocol for connecting cells within the consortia, conjugation will be used to send/receive more than mere 0/1 binary signals. Indeed, entire genetic circuits encoded in plasmid vectors will travel between cells and throughout the population. The project will engineer control strategies for such circuit mobility and demonstrate the potential for the application of resulting synthetic consortia: from population-based logic circuits and feedback loops to general-purpose biocomputers with environmental signals. Towards the successful implementation of the first wave (of many!) of conjugation-based multicellular computers.
Información adicional
Contactar con la unidad
CAPTCHA
Esta pregunta es para comprobar si usted es un visitante humano y prevenir envíos de spam automatizado.