Oxygen Homeostasis in the Cardiovascular System Lab


Cardiovascular diseases (CVDs) represent the main cause of death and their high prevalence implies an elevated healthcare cost, in addition to increasing physical dependence and reducing the quality of aging of the population. Many CVDs are associated with alterations in tissue and cellular oxygen balance, although the underlying molecular mechanisms remain elusive. Our group is focused on understanding the importance of oxygen homeostasis and hypoxic signaling in the CV system. To this aim, we develop translational strategies that combine the generation and study of genetic animal models that recapitulate CV pathologies, with the analysis of human samples. Our multidisciplinary research integrates various areas such as Developmental Biology, Genetics or Physiology and favors the collaboration of experts in Biology, Bioinformatics, Metabolism and Clinics, contributing to uncover the pathogenesis of CVDs.

Main specialization

Área de investigación:
Disciplina ERC:
  • LS - LIFE SCIENCES
  • LS4 Physiology, Pathophysiology and Endocrinology
Industrial Leadership:
  • 7. Other
  • 7.1. Other
Societal Challenges:
  • 1. Health, demographic change and wellbeing
  • 1.04. Understanding disease