Host-parasite interplay in pneumococcal infection

The increase in the appearance of resistant bacteria to traditional antibiotics is currently causing important problems in relation to infections caused by pathogens such as Streptococcus pneumoniae (pneumococcus), Pseudomonas aeruginosa or Haemophilus influenzae. These species are the major cause of lower respiratory tract infections and are responsible for millions of deaths annually worldwide. In our laboratory we are developing new molecular tools that lead to innovative therapies in order to suppress these resistance phenomena. The group is focused on the design and engineering of enzymes encoded by phages with bactericidal capacity against susceptible bacteria and in new compounds that affect targets located in the bacterial surface and barely explored up to now, as well as the use of state-of-the-art nanotechnological tools to enhance the antimicrobial effect of the mentioned molecules.

Main specialization

Scientific Area:
ERC discipline:
  • LS6 Immunity and Infection
Industrial Leadership:
  • 7. Other
  • 7.1. Other
Societal Challenges:
  • 1. Health, demographic change and wellbeing
  • 1.04. Understanding disease