Biochemistry and genetics of yeasts

Molecular Biology and Biochemistry of Yeasts
The group studies regulatory mechanisms of transcription of genes encoding enzymes implicated in energy metabolism as well as regulatory mechanisms of those enzymes in yeasts. An important regulatory mechanism discovered is the control exerted by trehalose-6-phosphate in glycolysis in different yeasts. Using yeast the group showed for the first time the existence of genes encoding trehalose biosynthetic enzymes in higher plants. Several contributions to the knowledge of the mechanisms of catabolite repression in different yeasts have also been done particularly using the non-conventional yeast Yarrowia lipolytica, a yeast important for its biotechnological uses and as experimental model of dimorphism. The group is also interested in the expression of heterologous proteins in yeast for different purposes.

Main specialization

Scientific Area:
ERC discipline:
  • LS1 Molecular and Structural Biology and Biochemistry
Industrial Leadership:
  • 4. Biotechnology
  • 4.2. Biotechnology-based industrial processes
Societal Challenges:
  • 7. Other
  • 7.1. Other