Noticias Agenda: Semana del 15 al 19 de enero de 2018 AGENDA_18-01-18_12325465.gcl 2018-01-18T17:22:03Z 2018-01-18T17:22:03Z <div class="description">18/01/2018</div><div class="body"><table border="1" align="right" width="200" cellspacing="1" cellpadding="1"> <tbody> <tr> <td style="text-align: center;"> <p><span style="font-size: small;"><span style="font-family: Arial;">DESCARGA DE MATERIAL</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/b4de5552-3c2a-44fa-9f91-499808a83e0e/Actos_presidencia_Semana%2520del%252015%2520al%252019%2520de%2520enero%2520de%25202018.pdf" target="_blank"><strong>Agenda</strong> (pdf.)</a></span></span></p> </td> </tr> </tbody> </table> <p class="ladillo" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;">Martes 16 de enero: </span></span><o:p></o:p></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;"><b>Inauguraci&oacute;n de la exposici&oacute;n </b><b>Las colinas de los dientes de sable</b></span></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;"><b>Resumen:</b> En esta exposici&oacute;n se realiza un recorrido por los m&aacute;s de 25 a&ntilde;os de trabajo de campo en los yacimientos encontrados en el Cerro de los Batallones (Torrej&oacute;n de Velasco, Madrid) y las investigaciones multidisciplinares que han sido llevadas a cabo en base a los descubrimientos realizados en estos yacimientos y que han permitido conocer las faunas y el ambiente del centro peninsular en el Mioceno superior.</span></span><span style="font-size: 12pt;"><o:p></o:p></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;"><b>Lugar y hora:</b> Museo Arqueol&oacute;gico Regional en Alcal&aacute; de Henares. Plaza de las Bernardas s/n. Alcal&aacute; de Henares. 19:30 horas.</span></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span><span style="font-size: 12pt;"><o:p></o:p></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;">Durante el acto, la presidenta del CSIC, Rosa Men&eacute;ndez, destac&oacute;: &ldquo;La exposici&oacute;n narra la historia de la Comunidad de Madrid, del Madrid de hace 9 millones de a&ntilde;os, un territorio por el que paseaban Mastodontes y Tigres dientes de Sable. Para muchos, narra tambi&eacute;n la historia de un grupo de investigadores e instituciones comprometidos con la comunicaci&oacute;n de la ciencia&rdquo;.</span></span><span style="font-size: 12pt;"><o:p></o:p></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span><span style="font-family: Arial;"><span style="font-size: 12pt;"><v:shapetype id="_x0000_t75" coordsize="21600,21600" o:spt="75" o:preferrelative="t" path="m@4@5l@4@11@9@11@9@5xe" filled="f" stroked="f"></v:shapetype></span></span></p> <p style="text-align: justify;"><span style="font-size: small;"> </span></p> <p class="Piedefoto" style="text-align: justify;"><v:shapetype id="_x0000_t75" coordsize="21600,21600" o:spt="75" o:preferrelative="t" path="m@4@5l@4@11@9@11@9@5xe" filled="f" stroked="f"><v:stroke joinstyle="miter"><v:formulas><v:f eqn="if lineDrawn pixelLineWidth 0"><v:f eqn="sum @0 1 0"><v:f eqn="sum 0 0 @1"><v:f eqn="prod @2 1 2"><v:f 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style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;"><b>Reuni&oacute;n con los sindicatos del CSIC</b></span></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;"><b>Resumen:</b> La presidenta del CSIC, Rosa Men&eacute;ndez, y el secretario general, Alberto Sereno, asisten a la primera reuni&oacute;n con la representaci&oacute;n sindical en el CSIC de CC.OO., UGT, Confederaci&oacute;n Intersindical Galega y CSI-CSIF. </span></span><span style="font-size: 12pt;"><o:p></o:p></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;"><b>Lugar y hora:</b> Sede central del CSIC. 10:00 horas.</span></span><span style="font-size: 12pt;"><o:p></o:p></span></p> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;">Durante la reuni&oacute;n, los integrantes del CSIC han tratado temas como el contrato de gesti&oacute;n, la carrera profesional en el CSIC y la visi&oacute;n del nuevo equipo directivo sobre el organismo y los nuevos proyectos a poner en marcha.</span></span></p> <table border="0" align="left" width="200" cellspacing="1" cellpadding="1"> <tbody> <tr> <td><img src="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/86d5051e-e964-44da-ba98-96625da60fbf/Montaje_web.jpg" width="800" height="300" alt="" /></td> </tr> </tbody> </table> <p class="Piedefoto" style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p></div> 2018-01-18T17:22:03Z Un estudio abre la vía a reincorporar genes beneficiosos perdidos durante la mejora vegetal ARABIDOPSIS_12324780.gcl 2018-01-16T15:17:48Z 2018-01-16T15:17:48Z <div class="description">16/01/2018</div><div class="body"><table width="200" cellspacing="1" cellpadding="1" border="1" align="right"> <tbody> <tr> <td> <p style="text-align: center;"><br /> DESCARGA DE MATERIAL</p> <p style="text-align: center;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/ba4f38b3-c189-48b1-8a22-1e8f44a57d73/15enero18arabidopsis.pdf" target="_blank"><strong>Nota de prensa</strong></a> (<em>400 kb</em>)</p> <p style="text-align: center;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/b2578b55-a79c-4644-a37e-259f7df24e06/Slide2.tiff" target="_blank"><strong>Imagen </strong></a>(<em>1,5 kb</em>)</p> </td> </tr> </tbody> </table> <p><!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:DoNotShowRevisions /> <w:DoNotPrintRevisions /> <w:DoNotShowMarkup /> <w:DoNotShowComments /> <w:DoNotShowInsertionsAndDeletions /> <w:DoNotShowPropertyChanges /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> 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style="font-family: Arial;">Un equipo con participaci&oacute;n de investigadores del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) profundiza en las bases moleculares que podr&iacute;an llegar a salvar la barrera biol&oacute;gica que se genera al cruzar variedades vegetales durante la mejora de los cultivos. 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mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--> <table width="450" cellspacing="1" cellpadding="1" border="0" align="left"> </table> <table width="450" cellspacing="1" cellpadding="1" border="0" align="left"> </table> <table width="450" cellspacing="1" cellpadding="1" border="0" align="left"> <tbody> <tr> <td> <p><img src="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/fb8ca0e7-6d97-43d4-b10f-4437d40eb382/foto_web450.jpg" alt="" width="450" height="246" align="left" /><span style="font-size: smaller;"><span style="font-family: Arial;">&nbsp;&nbsp; Anteras te&ntilde;idas con un marcador fluorescente (GERM&Aacute;N MART&Iacute;NEZ ARIAS)</span></span><!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState="false" 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<w:LsdException Locked="false" Priority="32" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Intense Reference" /> <w:LsdException Locked="false" Priority="33" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Book Title" /> <w:LsdException Locked="false" Priority="37" Name="Bibliography" /> <w:LsdException Locked="false" Priority="39" QFormat="true" Name="TOC Heading" /> </w:LatentStyles> </xml><![endif]--><!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--></p> </td> </tr> </tbody> </table> </p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">Durante el proceso de mejora de la mayor&iacute;a de los cultivos modernos, se produce una p&eacute;rdida de determinados genes, como los que participan en la resistencia a los pat&oacute;genos o al estr&eacute;s abi&oacute;tico. Adem&aacute;s, la mayor&iacute;a de las variedades que son seleccionadas son poliploides, es decir, tienen m&aacute;s de dos series de cromosomas.</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Los mejoradores pueden introducir dichos genes en las variedades actuales cruzando con las variedades ancestrales, pero al no ser &eacute;stas poliploides, se encuentran con una barrera de hibridaci&oacute;n complicada de superar, pues las semillas resultantes de cruces de variedades con diferente ploid&iacute;a &ndash;n&uacute;mero de juegos completos de cromosomas- resultan en aborto&rdquo;, explica Jordi Moreno, que trabaja en el Centro de Investigaci&oacute;n en Agrigen&oacute;mica (un consorcio <span class="st">p&uacute;blico formado por el CSIC, el IRTA, la Universidad Aut&oacute;noma de Barcelona y la Universidad de Barcelona)</span>.</span></span></p> <p class="ladillo"><strong><span style="font-size: small;"><span style="font-family: Arial;">Semillas viables</span></span></strong><span style="font-size: small;" /></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">En el trabajo, liderado por la Swedish University of Agricultural Sciences, en Uppsala (Suecia), los investigadores muestran que plantas mutantes que no son capaces de sintetizar un tipo de ARN denominado de silenciamiento (siRNA por sus siglas en ingl&eacute;s) pueden superar la barrera de la hibridaci&oacute;n. Por tanto, los cruces entre plantas de diferente ploid&iacute;a dan como resultado semillas viables.</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Los datos sugieren que un exceso de siRNA en el polen derivado de plantas poliploides provoca un fallo en el desarrollo de la semilla y, finalmente, su muerte. Este mecanismo es un claro ejemplo de que los siRNA de polen tienen un efecto posterior a la fertilizaci&oacute;n. Con ello se demuestra la importancia de los mecanismos de regulaci&oacute;n epigen&eacute;tica entre generaciones, cruciales para la estabilidad del genoma y la viabilidad de la semilla&rdquo;, concluye Moreno.</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">Durante los experimentos, los cient&iacute;ficos observaron que plantas de <i style="mso-bidi-font-style:normal">Arabidopsis</i> mutantes que eran deficientes en la biog&eacute;nesis de ciertos siRNA, compensaban el desequilibrio de ploid&iacute;a que ocurre al cruzar plantas diploides con polen de plantas tetraploides (donde el polen tiene un exceso de cromosomas paternos). Utilizando m&eacute;todos de secuenciaci&oacute;n masiva de siRNA, de ARN mensajero y metilaci&oacute;n de ADN, han podido analizar los mecanismos moleculares de este proceso. </span></span><span style="font-size: small;"><span style="font-family: Arial;">&nbsp;</span></span></p> <ul> <li><span style="font-size: smaller;"><span style="font-family: Arial;">German Martinez, Philip Wolff, Zhenxing Wang, Jordi Moreno-Romero, Juan Santos-Gonz&aacute;lez, Lei Liu Conze, Christopher DeFraia, R. Keith Slotkin, Claudia K&ouml;hler. <b style="mso-bidi-font-weight:normal"><span lang="EN-US">Paternal easiRNAs regulate parental genome dosage in Arabidopsis</span></b><span lang="EN-US">. <i style="mso-bidi-font-style:normal">Nature Genetics</i>. </span>DOI: 10.1038/s41588-017-0033-4</span></span><span style="font-family: Arial;" /></li> </ul> <p>&nbsp;</p></div> 2018-01-16T15:17:48Z Semana CSIC SEMANA_CSIC_12323774.gcl 2018-01-11T23:54:20Z 2018-01-11T23:54:20Z <div class="description">12/01/2018</div><div class="body"><table width="200" border="1" align="right" cellpadding="1" cellspacing="1"> <tbody> <tr> <td style="text-align: center;"> <p><span style="font-size: small;"><span style="font-family: Arial;">DESCARGA DE MATERIAL</span></span></p> <p><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/f4e5b306-64e4-47a1-b505-516b048baf39/Eventos_12_01_18.pdf"><strong><span style="font-size: small;"><span style="font-family: Arial;">Nota de prensa</span></span></strong><span style="font-size: small;"><span style="font-family: Arial;"> (pdf.)</span></span></a></p> </td> </tr> </tbody> </table> <p><span style="font-size: small;"><span style="font-family: Arial;">Reuni&oacute;n con centros y directores de CCHS</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Reuni&oacute;n del CSIC con Cepsa</span></span></p> <p>&nbsp;</p></div> 2018-01-11T23:54:20Z Rosa Menéndez, elegida “Asturiana del mes” por La Nueva España ROSA_MENÉNDEZ_ASTURIANA_12323260.gcl 2018-01-09T09:01:55Z 2018-01-09T09:01:55Z <div class="description">09/01/2018</div><div class="body"><table width="200" border="1" align="right" cellpadding="1" cellspacing="1"> <tbody> <tr> <td> <p style="text-align: center;"><span style="font-size: small;"><span style="font-family: Arial;"><strong>DESCARGA DE MATERIAL</strong></span></span><span style="font-family: Arial;" /></p> <p style="text-align: center;"><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/a1c15c6d-3f82-4c87-a525-6876711960a6/Rosa%2520Men%25c3%25a9ndez%2520LNE.pdf">Nota de prensa (pdf)</a></span></span></p> <p style="text-align: center;"><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/680c6724-ca21-4ea8-9a3a-a1e22323a17d/Rosa_Menendez1.JPG">Imagen (jpeg)</a></span></span></p> </td> </tr> </tbody> </table> <p><span style="font-size: small;"><span style="font-family: Arial;">La presidenta del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC), Rosa Men&eacute;ndez (Cudillero, Asturias, 1956), ha sido elegida <a href="http://www.lne.es/sociedad/2018/01/07/rosa-menendez-nueva-presidenta-csic/2218892.html">&ldquo;Asturiana del mes&rdquo; de diciembre por el peri&oacute;dico <i>La Nueva Espa&ntilde;a</i></a>. Seg&uacute;n el diario, Men&eacute;ndez recibe la distinci&oacute;n &ldquo;por ser la primera mujer al frente de la entidad estatal&rdquo;, adem&aacute;s de &ldquo;por su trayectoria profesional en distintas funciones del CSIC, al que lleva vinculada desde 1979&rdquo;. El peri&oacute;dico tambi&eacute;n reconoce la experiencia de Men&eacute;ndez en la gesti&oacute;n institucional.&nbsp;</span></span></p> <table width="500" border="0" align="left" cellpadding="1" cellspacing="1"> <tbody> <tr> <td> <p><img src="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/00160b87-2a7b-49cc-8cbb-6ce0d2c8151a/Foto%2520interior%2520500.jpg" width="500" height="333" alt="" /><span style="font-size: smaller;"><span style="font-family: Arial;">Rosa Men&eacute;ndez, presidenta del CSIC./ Foto: CSIC Comunicaci&oacute;n</span></span></p> </td> </tr> </tbody> </table> <p><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p class="cuerpodetexto"><o:p></o:p></p></div> 2018-01-09T09:01:55Z Demuestran que el agua se mantiene líquida a 43 grados bajo cero AGUA_SUBENFRIADA_12323246.gcl 2018-01-08T09:54:03Z 2018-01-08T09:54:03Z <div class="description">08/01/2018</div><div class="body"><table width="200" cellspacing="1" cellpadding="1" border="1" align="right"> <tbody> <tr> <td> <p style="text-align: center;"><span style="font-size: small;"><span style="font-family: Arial;" /></span><br /> <span style="font-size: small;"><span style="font-family: Arial;">DESCARGA DE MATERIAL</span></span></p> <p style="text-align: center;"><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/9b8f3bae-33f7-4c98-b3c4-10ab59c9d353/08enero18agua_subenfriada.pdf" target="_blank"><strong>Nota de prensa</strong></a> (<em>384 kb</em>)<br /> </span></span></p> </td> </tr> </tbody> </table> <p><span style="font-size: small;"><span style="font-family: Arial;"><!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:DoNotShowRevisions /> <w:DoNotPrintRevisions /> <w:DoNotShowMarkup /> <w:DoNotShowComments /> <w:DoNotShowInsertionsAndDeletions /> <w:DoNotShowPropertyChanges /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>ES</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:EnableOpenTypeKerning /> <w:DontFlipMirrorIndents /> <w:OverrideTableStyleHps /> </w:Compatibility> <m:mathPr> <m:mathFont m:val="Cambria Math" /> <m:brkBin m:val="before" /> <m:brkBinSub m:val="&#45;-" /> <m:smallFrac m:val="off" /> <m:dispDef /> <m:lMargin m:val="0" /> <m:rMargin m:val="0" /> <m:defJc m:val="centerGroup" /> <m:wrapIndent m:val="1440" /> <m:intLim m:val="subSup" /> <m:naryLim m:val="undOvr" /> </m:mathPr></w:WordDocument> </xml><![endif]-->&iquest;Hasta qu&eacute; punto es posible enfriar el agua sin que se congele? Es una pregunta que los cient&iacute;ficos que estudian las propiedades an&oacute;malas del H<sub>2</sub>O, que pueden afectar al clima y que han sido clave en preservar la vida en el planeta, se han hecho muchas veces. Un equipo con participaci&oacute;n de investigadores del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) ha arrojado luz a esta cuesti&oacute;n al demostrar que el agua l&iacute;quida pura puede existir a 43 grados bajo cero, el m&iacute;nimo alcanzado hasta ahora. 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Name="Bibliography" /> <w:LsdException Locked="false" Priority="39" QFormat="true" Name="TOC Heading" /> </w:LatentStyles> </xml><![endif]--><!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]-->Claudia Goy, Marco A. C. Potenza, Sebastian Dedera, Marilena Tomut, Emmanuel Guillerm, Anton Kalinin, Kay-Obbe Voss, Alexander Schottelius, Nikolaos Petridis, Alexey Prosvetov, Guzm&aacute;n Tejeda, Jos&eacute; M. Fern&aacute;ndez, Christina Trautmann, Fr&eacute;d&eacute;ric Caupin, Ulrich Glasmacher, and Robert E. Grisenti. <b style="mso-bidi-font-weight:normal"><span lang="EN-US">Shrinking of Rapidly Evaporating Water Microdroplets Reveals their Extreme Supercooling</span></b><span lang="EN-US">. <i style="mso-bidi-font-style:normal">Physical Review Letters</i>. 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font-family:"Times New Roman","serif";} </style> <![endif]--></p></div> 2018-01-08T09:54:03Z Tres investigadores del CSIC ingresan en la Real Academia de Ciencias y Artes de Barcelona INVESTIGADORES_RACAB_12316829.gcl 2018-01-02T10:30:14Z 2018-01-02T10:30:14Z <div class="description">02/01/2018</div><div class="body"><table width="200" border="1" align="right" cellpadding="1" cellspacing="1"> <tbody> <tr> <td> <p style="text-align: center;"><strong><span style="font-size: small;"><span style="font-family: Arial;">DESCARGA DE MATERIAL</span></span></strong><span style="font-size: small;" /></p> <p style="text-align: center;"><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/ad44f737-29ec-474c-bbba-81878f6a0319/2enero2018%2520miembros%2520RACAB.pdf">Nota de prensa (pdf)</a></span></span></p> <p style="text-align: center;"><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/80417865-2de3-4ffc-9c1e-bb568390725b/Foto_premio_RACAB.jpg">Imagen (jpeg)</a></span></span></p> </td> </tr> </tbody> </table> <p><span style="font-size: small;"><span style="font-family: Arial;">Tres investigadores del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC), Francesc Piferrer (genetista), Xavier Querol (ge&oacute;logo) y Enric Canadell (qu&iacute;mico), han sido elegidos miembros de la <a href="http://www.racab.es/es/">Real Academia de Ciencias y Artes de Barcelona</a>, una instituci&oacute;n destinada a promover la ciencia, la t&eacute;cnica y el arte en el &aacute;mbito de la cultura y la sociedad. Fue fundada en 1764 y aglutina a profesionales de la ciencia y las artes aplicadas.</span></span><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p>&nbsp;</p> <table width="500" border="0" align="left" cellpadding="1" cellspacing="1"> <tbody> <tr> <td> <p><img src="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/1b56b21a-f62a-4587-846f-78f93c961647/Foto%2520interior%2520500.jpg" width="500" height="333" alt="" /><span style="font-size: smaller;"><span style="font-family: Arial;">Los investigadores Xavier Querol, Francesc Piferrer y Enric Canadell./ CSIC Comunicaci&oacute;n</span></span></p> </td> </tr> </tbody> </table> <p>&nbsp;</p></div> 2018-01-02T10:30:14Z Las bacterias del suelo pueden variar la composición de los ecosistemas BACTERIAS_Y_PLANTAS_12310588.gcl 2017-12-19T10:58:49Z 2017-12-19T10:58:49Z <div class="description">19/12/2017</div><div class="body"><table width="200" border="1" align="right" cellpadding="1" cellspacing="1"> <tbody> <tr> <td style="text-align: center;"> <p><span style="font-size: small;"><span style="font-family: Arial;">DESCARGA DE MATERIAL</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/f6b90685-7597-49d1-a0bb-dd740af6a08a/19diciembre2017_Bacterias_plantas.pdf" target="_blank"><strong>Nota de prensa</strong> (pdf.)</a></span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/953f5a21-778a-4e15-8c27-2869212404f5/Arto%2520y%2520cambr%25c3%25b3n%2520.jpg"><strong>Imagen</strong> (jpg.)</a></span></span></p> </td> </tr> </tbody> </table> <p style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span><span style="font-size: small;"><span style="font-family: Arial;">Una investigaci&oacute;n en la que han participado cient&iacute;ficos del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) ha demostrado que las bacterias del suelo cambian cuando dos especies de plantas interact&uacute;an, lo que afecta al rendimiento de una de las especies, que puede incluso llegar a desaparecer de la zona. Los resultados obtenidos muestran la importancia de los microbios en la composici&oacute;n y funcionamiento de los ecosistemas.</span></span></p> <table width="200" border="1" align="left" cellpadding="1" cellspacing="1"> <tbody> <tr> <td><img src="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/953f5a21-778a-4e15-8c27-2869212404f5/Arto%2520y%2520cambr%25c3%25b3n%2520.jpg" width="500" height="279" alt="" /></td> </tr> </tbody> </table> <p style="text-align: justify;"><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> <ul> <li> <p class="Referencias"><span style="font-size: smaller;"><span style="font-family: Arial;">Hortal S. Lozano Y.M., Bastida F., Armas C., Moreno J.L., Garc&iacute;a C., Puignaire F.I. <b>Plant-plant competition outcomes are modulated by plant effects on the soil bacterial community. </b><i>Scientific Reports</i>. DOI:10.1038/S41598-017-18103-5</span></span><o:p></o:p></p> </li> </ul> <p class="cuerpodetexto"><o:p></o:p></p></div> 2017-12-19T10:58:49Z Descubierto un segundo anillo en la nebulosa del insecto NEBULOSA_INSECTO_12238895.gcl 2016-09-22T07:38:10Z 2016-09-22T07:38:10Z <div class="description">22/09/2016</div><div class="body"><table width="200" cellspacing="1" cellpadding="1" border="1" align="right"> <tbody> <tr> <td style="text-align: center;"> <p><strong>DESCARGA DE MATERIAL</strong></p> <p><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/d97a6fc7-16e2-4671-a4c9-0acf1484fcd0/22septiembre2016nebulosainsecto.pdf" target="_blank">Nota de prensa</a> (pdf 500K)</p> <p><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/fce0cfb7-84ff-40f7-8ad6-c5195b62319c/butterfly_nebula_NASA_ESA_Hubble.jpg" target="_blank">Imagen</a> <em>(jpg 1,1M)</em></p> </td> </tr> </tbody> </table> <p><!--[if gte mso 9]><xml> 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mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--><span style="font-size: small;"><span style="font-family: Arial;">Un equipo de investigadores liderado por el Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) ha descubierto un segundo anillo en la Nebulosa del Insecto (NGC 6302), situada a unos 3.400 a&ntilde;os luz de la Tierra. 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table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--></p> </td> </tr> </tbody> </table> <p><!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>ES</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:EnableOpenTypeKerning /> <w:DontFlipMirrorIndents /> <w:OverrideTableStyleHps /> </w:Compatibility> <m:mathPr> <m:mathFont m:val="Cambria Math" /> <m:brkBin m:val="before" /> <m:brkBinSub m:val="&#45;-" /> <m:smallFrac m:val="off" /> <m:dispDef /> <m:lMargin m:val="0" /> <m:rMargin m:val="0" /> <m:defJc m:val="centerGroup" /> <m:wrapIndent m:val="1440" /> <m:intLim m:val="subSup" /> <m:naryLim m:val="undOvr" /> </m:mathPr></w:WordDocument> </xml><![endif]--><span style="font-size: small;"><span style="font-family: Arial;">Numerosas enfermedades autoinmunes se caracterizan por la presencia de linfocitos B autorreactivos con capacidad para reconocer ant&iacute;genos propios y ocasionar da&ntilde;os en los tejidos del individuo. Nuestro sistema inmunitario tiene diversos mecanismos para eliminar estas c&eacute;lulas autorreactivas que pueden ocasionar el desarrollo de enfermedades autoinmunes, como lupus eritematoso sist&eacute;mico, artritis reumatoide, diabetes y esclerosis m&uacute;ltiple. Un estudio con participaci&oacute;n del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) y publicado en la revista <i style="mso-bidi-font-style: normal">Nature Immunology</i> desvela un regulador clave en este proceso. Seg&uacute;n los resultados de este trabajo, el aumento de expresi&oacute;n de la mol&eacute;cula micro ARN 148a (miR-148a) facilita la supervivencia de linfocitos B autorreactivos, que deber&iacute;an ser eliminados, desencadenando as&iacute; el desarrollo de lupus.</span></span></p> <p><!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState="false" DefUnhideWhenUsed="true" DefSemiHidden="true" DefQFormat="false" DefPriority="99" LatentStyleCount="267"> <w:LsdException Locked="false" Priority="0" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Normal" /> <w:LsdException Locked="false" Priority="0" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="heading 1" /> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 2" /> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 3" /> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 4" /> <w:LsdException Locked="false" Priority="9" QFormat="true" 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mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">Los micro-ARN son mol&eacute;culas de ARN de 19 a 23 nucle&oacute;tidos capaces de regular la expresi&oacute;n de ciertos genes diana. Para conseguirlo se unen a secuencias complementarias del ARN mensajero e inducen su degradaci&oacute;n, de modo que la prote&iacute;na no llega a producirse. Este estudio demuestra que miR-148a modula la expresi&oacute;n de tres prote&iacute;nas importantes para regular la tolerancia de los linfocitos B y prevenir la autoinmunidad: Bim, PTEN y GADD45a.</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Estudios previos hab&iacute;an mostrado un aumento significativo de la expresi&oacute;n de miR-148a en linfocitos B de pacientes con lupus, pero no se hab&iacute;a demostrado una relaci&oacute;n causa-efecto entre el aumento en la expresi&oacute;n y el desarrollo de la patolog&iacute;a.&nbsp; Tampoco se conoc&iacute;a a trav&eacute;s de qu&eacute; mecanismo este miRNA pod&iacute;a influir en el desarrollo de la misma. En este trabajo se describe por primera vez c&oacute;mo un miRNA controla los procesos de eliminaci&oacute;n de linfocitos B autorreactivos&rdquo;, explica Jes&uacute;s &nbsp;Salvador, investigador del CSIC en el Centro Nacional de Biotecnolog&iacute;a. &nbsp;</span></span></p> <h3><span style="font-size: small;"><span style="font-family: Arial;">Prevenci&oacute;n de la autoinmunidad <span style="color: rgb(38, 38, 38);" /></span></span></h3> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;La funci&oacute;n de las prote&iacute;nas Bim y PTEN para prevenir la autoinmunidad ya era conocida en el campo, sin embargo este estudio es pionero ha identificado por primera vez la funci&oacute;n del gen supresor de autoinmunidad GADD45a en el control de la tolerancia central de linfocitos B. Los ratones deficientes en esta prote&iacute;na desarrollan espont&aacute;neamente una enfermedad similar al lupus eritematoso sist&eacute;mico&rdquo; destaca Jes&uacute;s Salvador.</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">Seg&uacute;n el estudio, al aumentar la expresi&oacute;n de miR-148a en un modelo murino de lupus<span style="color: red;"> </span>(proceso frecuente en pacientes con lupus eritomatoso o artritis reumatoide) el desarrollo de la enfermedad autoinmune se aceler&oacute; ocasionando la muerte prematura. &ldquo;Conocer los mecanismos que controlan la autotolerancia puede llevar a nuevas estrategias para el tratamiento de la autoinmunidad&rdquo;, concluye el investigador.</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">El estudio<span style="color: red;"> </span>se ha realizado en el Instituto de Investigaci&oacute;n The Scripps (Estados Unidos) en colaboraci&oacute;n con la Universidad de Yale (Estados Unidos) y el Centro Nacional de Biotecnolog&iacute;a del CSIC.</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">&nbsp;</span></span></p> </p> <ul> <li><span style="font-size: small;"><span style="font-family: Arial;"> </span><span style="font-size: smaller;"><span style="font-family: Arial;">Alicia Gonzalez-Martin, Brian D Adams, Maoyi Lai, Jovan Shepherd, Maria Salvador-Bernaldez, Jesus M Salvador, Jun Lu, David Nemazee &amp; Changchun Xiao. <b style="mso-bidi-font-weight:normal"><span lang="EN-US">The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity</span></b><span lang="EN-US">. <i style="mso-bidi-font-style:normal">Nature </i></span><i style="mso-bidi-font-style: normal">Immunology. </i>DOI:<i style="mso-bidi-font-style:normal"> </i>10.1038/ni.3385</span></span></span><span style="font-family: Arial;" /></li> </ul> <p><a target="_blank" href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/353b8bc5-4513-465c-bde5-45a38e5e44a3/22febrero2016microARN.pdf"><span style="font-size: small;"><span style="font-family: Arial;"><strong>Nota de prensa</strong></span></span><span style="font-family: Arial;" /></a> <em>(pdf 440K)</em></p> <p><strong><span style="font-size: small;"><span style="font-family: Arial;"><a target="_blank" href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/d7de84a3-a806-4869-a382-02d211ae461f/imagen_lupus.jpg">Imagen</a> </span></span></strong><em><span style="font-size: small;"><span style="font-family: Arial;">(jpg K)</span></span></em><span style="font-size: small;" /></p></div> 2016-02-22T16:38:24Z La misión CHEOPS anuncia los dibujos de niños españoles que viajarán al espacio CHEOPS_GANADORES_12173097.gcl 2016-02-22T09:08:50Z 2016-02-22T09:08:50Z <div class="description">22/02/2016</div><div class="body"><table cellspacing="1" cellpadding="1" border="0" width="450" align="right"> <tbody> <tr> <td> <p><img height="272" width="450" alt="" src="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/f61e0f0c-3d8a-4f10-9fd4-b9f7d3c24914/fotonota.jpg" /><br /> <!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>ES</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> 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SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Intense Reference" /> <w:LsdException Locked="false" Priority="33" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Book Title" /> <w:LsdException Locked="false" Priority="37" Name="Bibliography" /> <w:LsdException Locked="false" Priority="39" QFormat="true" Name="TOC Heading" /> </w:LatentStyles> </xml><![endif]--><!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">El certamen de dibujos infantiles ha sido una iniciativa de la Agencia Espacial Europea para acercar el desarrollo espacial a los m&aacute;s peque&ntilde;os y que en Espa&ntilde;a cuenta con la colaboraci&oacute;n del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC), el Institut d&rsquo;Estudis Espacials de Catalunya&nbsp; y el Instituto de Astrof&iacute;sica de Canarias .</span></span></p> <h3><span style="font-size: small;"><span style="font-family: Arial;">3.000 dibujos viajar&aacute;n al espacio</span></span></h3> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">En total, unos 3.000 dibujos de ni&ntilde;os europeos de entre 8 y 14 a&ntilde;os ser&aacute;n miniaturizados y grabados en una placa que ir&aacute; montada en el telescopio espacial CHEOPS. &ldquo;Gracias a este concurso y al proyecto CHEOPS miles de ni&ntilde;os podr&aacute;n cumplir su sue&ntilde;o de, en cierto modo, viajar al espacio y surcarlo en busca de otros mundos&rdquo;, se&ntilde;ala Ignasi Ribas, investigador del CSIC y del Institut d&rsquo;Estudis Espacials de Catalunya en el Instituto de Ciencias del Espacio y coordinador de la iniciativa en Espa&ntilde;a.</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">El certamen, cuyo objetivo ha sido acercar la astronom&iacute;a y la ciencia a los m&aacute;s peque&ntilde;os, ha superado todas las expectativas de los organizadores en cuanto a participaci&oacute;n y calidad de las obras. Gracias a la gran cantidad de dibujos recibidos, el n&uacute;mero asignado a Espa&ntilde;a fue aumentado de 250 a 297. Los requisitos para participar consist&iacute;an en que los trabajos presentados deb&iacute;an estar inspirados en el espacio o en el telescopio CHEOPS y ser en blanco y negro, para poder transferirse correctamente a la placa. </span></span></p> <h3><span style="font-size: small;"><span style="font-family: Arial;">La misi&oacute;n CHEOPS<span style="color: rgb(38, 38, 38);" /></span></span></h3> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">El nombre de<i>&nbsp;</i>CHEOPS&nbsp;es un homenaje al Antiguo Egipto y una referencia a la pir&aacute;mide Keops. Hasta el momento se han descubierto unos 2.000 exoplanetas y con esta misi&oacute;n espacial, perteneciente al programa&nbsp;<i>Cosmic Vision</i>&nbsp;de la Agencia Espacial Europea, se pretende aumentar este n&uacute;mero y a la vez obtener medidas mucho m&aacute;s precisas de aquellos que ya se conocen. &nbsp;</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">El telescopio&nbsp;CHEOPS&nbsp;se dedicar&aacute; a observar tr&aacute;nsitos de planetas, es decir, peque&ntilde;os eclipses en estrellas brillantes en las que ya se sabe que existe un sistema planetario. Se har&aacute; mediante fotometr&iacute;a de muy alta precisi&oacute;n, una t&eacute;cnica con la que se mide el brillo de una estrella cada minuto y se detecta una disminuci&oacute;n cuando, en su movimiento orbital, el planeta pasa por delante y oculta parte del disco de la estrella. Dichos datos permitir&aacute;n determinar con gran precisi&oacute;n el tama&ntilde;o del planeta y saber si se trata de un mundo de gas, como Neptuno, o de roca, como la Tierra.</span></span></p> <p class="cuerpodetexto"><span style="font-size: small;"><span style="font-family: Arial;">Esta misi&oacute;n es la primera de la Agencia Espacial Europea en la categor&iacute;a de peque&ntilde;a misi&oacute;n. Existen tres rangos: las grandes, que cuestan miles de millones de euros; las medianas, aquellas que cuestan cientos de millones y, por &uacute;ltimo, las peque&ntilde;as, de menos de 100 millones.&nbsp;CHEOPS&nbsp;fue seleccionada entre 26 propuestas en octubre de 2012 y cuenta con un presupuesto de 50 millones de euros.</span></span></p> <p class="enlaces"><a target="_blank" href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/5584e18a-3fc6-4a82-a745-72d1f492ec95/22febrero2016cheops.pdf"><strong><span style="font-size: small;"><span style="font-family: Arial;">Nota de prensa</span></span></strong></a><span style="font-size: small;"><span style="font-family: Arial;"> (.pdf)<br /> </span></span></p> <p class="enlaces"><strong><span style="font-size: small;"><span style="font-family: Arial;">V&iacute;deo:</span></span><i><span style="font-size:11.0pt;font-family:&quot;Calibri&quot;,&quot;sans-serif&quot;" /></i></strong><b><i><span style="font-size:11.0pt;font-family:&quot;Calibri&quot;,&quot;sans-serif&quot;"> <a href="https://webmail.csic.es/bigfiles/descarga.php?l=78720904t&amp;t=1456129940&amp;f=CheopsFLV.flv"><span style="font-size: small;"><span style="font-family: Arial;">resoluci&oacute;n web </span></span></a></span></i></b><i><span style="font-size:11.0pt;font-family:&quot;Calibri&quot;,&quot;sans-serif&quot;"><a href="https://webmail.csic.es/bigfiles/descarga.php?l=78720904t&amp;t=1456129940&amp;f=CheopsFLV.flv"><span style="font-size: small;"><span style="font-family: Arial;">(.flv)</span></span></a><span style="font-size: small;"><span style="font-family: Arial;" /></span></span></i><b><i><span style="font-size:11.0pt;font-family:&quot;Calibri&quot;,&quot;sans-serif&quot;"><span style="font-size: small;"><span style="font-family: Arial;"> / </span></span><a href="https://webmail.csic.es/bigfiles/descarga.php?l=78720904t&amp;t=1456129940&amp;f=Cheops.mov"><span style="font-size: small;"><span 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<w:LsdException Locked="false" Priority="37" Name="Bibliography" /> <w:LsdException Locked="false" Priority="39" QFormat="true" Name="TOC Heading" /> </w:LatentStyles> </xml><![endif]--><!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> <![endif]--></p> <p>&nbsp;</p></div> 2016-02-22T09:08:50Z Desarrollan un nuevo tipo de guisante que facilita la digestión de proteínas GUISANTE_DIGESTIVO_12129557.gcl 2015-08-23T22:58:59Z 2015-08-23T22:58:59Z <div class="description">24/08/2015</div><div class="body"><p><span style="font-size: small;"><span style="font-family: Arial;">Un equipo de investigaci&oacute;n internacional con participaci&oacute;n del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) ha obtenido guisantes que facilitan la digesti&oacute;n de prote&iacute;nas y que pueden ser utilizados de manera m&aacute;s eficaz en la elaboraci&oacute;n de piensos para animales. Los resultados del estudio se publican en la revista <i>PLoS ONE</i>.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Los guisantes y otras leguminosas tales como el garbanzo, la lenteja o la soja, contienen inhibidores de proteasas que bloquean la digesti&oacute;n de las prote&iacute;nas, dificultando su absorci&oacute;n intestinal. Estudios nutricionales previos llevados a cabo con pollos broiler (alimentados a gran escala para la producci&oacute;n espec&iacute;fica de carne) han mostrado que elevadas concentraciones de estos inhibidores en la dieta pueden reducir la disponibilidad de prote&iacute;nas en un 10 %. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Ahora los investigadores han obtenido guisantes que presentan un contenido reducido o nulo de estos inhibidores de proteasas, lo cual ha sido perseguido durante mucho tiempo tanto por mejoradores de plantas como por fabricantes de piensos&rdquo;, seg&uacute;n explica Alfonso Clemente, investigador del CSIC en la Estaci&oacute;n Experimental del Zaid&iacute;n.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;En este trabajo hemos investigado si mutaciones inducidas o naturales presentes en los inhibidores de proteasas pueden ser explotadas para mejorar la calidad de las semillas de guisante&rdquo;, se&ntilde;ala Clemente. &ldquo;As&iacute;, hemos identificado y estudiado l&iacute;neas de guisante que presentan mutaciones puntuales&rdquo;. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;De las tres mutaciones inducidas estudiadas, una de ellas imposibilita la capacidad de las prote&iacute;nas estudiadas de inhibir a las proteasas digestivas, tripsina y quimotripsina, mientras que las otras dos mutaciones afectan, aunque en menor grado, su actividad inhibidora&rdquo;, sostiene Clemente. Los resultados obtenidos nos han permitido ahondar en la relaci&oacute;n existente entre estructura proteica y actividad inhibidora de proteasas que pudiera influir en la calidad de la semilla de guisante, a&ntilde;ade el investigador.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Asimismo, se ha descrito una l&iacute;nea silvestre de guisante que al tener mutados dos genes, que codifican inhibidores mayoritarios de la semilla de guisante, carece de actividad inhibidora. Esta l&iacute;nea mutante silvestre (<i>Pisum elatius</i>) ha sido cruzada satisfactoriamente con la especie cultivada (<i>Pisum sativum</i>).&nbsp; </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Estos guisantes no difieren sensorialmente de los convencionales, tienen mejorada su digestibilidad proteica y el hecho de que no hayan sido obtenidos mediante modificaci&oacute;n gen&eacute;tica les permitir&iacute;a estar en el mercado en un periodo de tiempo no superior a cinco a&ntilde;os&rdquo;, se&ntilde;ala el investigador.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Estos estudios podr&iacute;an ser extendidos a otras prote&iacute;nas vegetales, que pudieran presentar efectos nutricionales negativos, tales como los al&eacute;rgenos. La reducci&oacute;n o eliminaci&oacute;n de prote&iacute;nas anti-nutricionales podr&iacute;a mejorar la calidad de las semillas de leguminosas destinadas a nutrici&oacute;n animal y humana, detalla el investigador.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">El consorcio internacional est&aacute; constituido por investigadores del John Innes Centre (Reino Unido), INRA (Francia), CSIC y de la empresa IDna Genetics Ltd.</span></span></p> <p>&nbsp;</p> <ul> <li><span style="font-size: smaller;"><span style="font-family: Arial;">Alfonso Clemente, Maria C. Arques, Marion Dalmais, Christine Le Signor, Catherine Chinoy, Raquel Olias, Tracey Rayner, Peter G. Isaac, David M. Lawson, Abdelhafid Bendahmane, Claire Domoney. <b>Eliminating Anti-nutritional Plant Food Proteins: The Case of Seed Protease Inhibitors in Pea</b>. <i>PLoS ONE.</i> Doi:10.1371/journal.pone.0134634&nbsp;&nbsp;</span></span></li> </ul> <p><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/f3e63bea-e2a0-4de9-b71c-a9d53aeb1274/24agosto2015%2520guisante%2520digestivo.pdf"><span style="font-family: Arial;" /><strong><span style="font-size: small;"><span style="font-family: Arial;">Nota de prensa</span></span></strong><span style="font-size: small;"><span style="font-family: Arial;"> </span><em><span style="font-family: Arial;">(pdf 546K)</span></em></span></a></p> <p><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/a5ded928-422d-4489-af22-86e3e390d9b6/Seeds-pea%2520only.jpg"><strong><span style="font-size: small;"><span style="font-family: Arial;">Descarga de imagen: muestras de guisantes</span></span></strong><span style="font-size: small;"><span style="font-family: Arial;"> </span><em><span style="font-family: Arial;">(jpeg 575K)</span></em></span></a></p></div> 2015-08-23T22:58:59Z Describen por primera vez la comunidad de virus ARN en la Antártida VIRUS_ANTARTIDA_12124758.gcl 2015-08-23T22:58:58Z 2015-08-23T22:58:58Z <div class="description">12/08/2015</div><div class="body"><p><span style="font-size: small;"><span style="font-family: Arial;">Los virus de ARN usan &aacute;cido ribonucleico (ARN) como material gen&eacute;tico. Existen como mezclas complejas de genotipos diferentes pero relacionados, conocidas como quasiespecies. Su estructura gen&eacute;tica ha sido estudiada en los virus que afectan a los animales y plantas pero las quasiespecies no se han descrito en virus ARN de muestras ambientales. Ahora, un estudio del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) ha conseguido describir por primera vez quasiespecies de virus de ARN en un ecosistema natural, concretamente en el lago Limnopolar de la Pen&iacute;nsula Byers (Isla Livingston, en la Ant&aacute;rtida). Se trata adem&aacute;s de la primera descripci&oacute;n de virus ARN en la Ant&aacute;rtida.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;" /></span> <table width="600" cellspacing="1" cellpadding="1" border="0" align="center"> <tbody> <tr> <td><img width="600" height="273" alt="" title="Investigadores en el lago Limnopolar, situado en la Isla Livingston, en la Ant&aacute;rtida. (Manuel Toro/CSIC) " src="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/7ad03a9c-f8ae-4c64-bf2f-14222ecd9e59/antartida_np.jpg" /><br /> <!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>ES</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:EnableOpenTypeKerning /> <w:DontFlipMirrorIndents /> <w:OverrideTableStyleHps /> </w:Compatibility> <m:mathPr> <m:mathFont m:val="Cambria Math" /> <m:brkBin m:val="before" /> <m:brkBinSub m:val="&#45;-" /> <m:smallFrac m:val="off" /> <m:dispDef /> <m:lMargin m:val="0" /> <m:rMargin m:val="0" /> <m:defJc m:val="centerGroup" /> <m:wrapIndent m:val="1440" /> <m:intLim m:val="subSup" /> <m:naryLim m:val="undOvr" /> </m:mathPr></w:WordDocument> </xml><![endif]--> <p style="text-align: center;" class="Piedefoto"><span style="font-size: smaller;"><span style="font-family: Arial;">Investigadores en el lago Limnopolar, situado en la Isla Livingston, en la Ant&aacute;rtida. 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</tr> </tbody> </table> </p> <p><span style="font-size: small;"><span style="font-family: Arial;" /></span><span style="font-size: small;"><span style="font-family: Arial;">Los resultados, que son fruto de tres a&ntilde;os de investigaciones y se han publicado como art&iacute;culo destacado en la revista <i>Molecular Ecology</i>, indican que la diversidad de los virus de ARN es menor que la registrada en virus de ADN. En 2009, cient&iacute;ficos del mismo grupo de investigaci&oacute;n fueron los primeros en identificar la composici&oacute;n gen&eacute;tica de los virus ADN presentes en los lagos de la Ant&aacute;rtida. Estos estudios estimaron la presencia de cerca de 10.000 especies virales en el lago Limnopolar. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Solo hemos encontrado virus del orden <i>Picornavirales</i> y hemos identificado tambi&eacute;n algunos virus dominantes en el lago. En algunos casos, hasta el 70% de los virus encontrados se corresponden con una &uacute;nica especie, algo muy peculiar&rdquo;, se&ntilde;ala Antonio Alcam&iacute;, cient&iacute;fico del CSIC en el Centro de Biolog&iacute;a Molecular Severo Ochoa (centro mixto del CSIC y la Universidad Aut&oacute;noma de Madrid) y responsable del estudio. &ldquo;Este virus dominante se ha mantenido abundante y estable gen&eacute;ticamente durante tres a&ntilde;os, lo que sugiere que ha encontrado un genoma optimizado -la soluci&oacute;n evolutiva casi perfecta- para dominar el ecosistema extremo de este lago&rdquo;, explica.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Los lagos ant&aacute;rticos permanecen cubiertos de hielo durante la mayor parte del a&ntilde;o y tienen muy poca influencia de animales. Sus ecosistemas son muy sencillos y est&aacute;n dominados por microorganismos que se han adaptado a las condiciones ambientales extremas. La pen&iacute;nsula Byers es una de las pozas zonas de la Ant&aacute;rtida que se descongela durante el verano. La transici&oacute;n de un lago cubierto de hielo en primavera a un lago abierto en verano da lugar a cambios notables en la comunidad viral.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Este deshielo ha permitido a los investigadores detectar un fen&oacute;meno que no se conoc&iacute;a en la microbiolog&iacute;a ambiental: los virus generan m&aacute;s variaciones para adaptarse a un nuevo ambiente y competir con los virus que ya habitan este medio. As&iacute; ocurre con los virus que viven en los tapetes microbianos en la superficie de la cuenca. Estos tapetes son estructuras primitivas que se encuentran en la actualidad en ambientes extremos pero hace millones de a&ntilde;os generaron la atm&oacute;sfera de ox&iacute;geno de la Tierra. Cuando se produce el deshielo, los virus que habitan los tapetes son arrastrados al lago. Al encontrarse en un ambiente extra&ntilde;o sufren una mayor variaci&oacute;n que podr&iacute;a ayudarles a competir con los virus dominantes en el lago.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Este proyecto ha sido financiado por el Programa Polar del Ministerio de Econom&iacute;a y Competitividad, y la expedici&oacute;n fue posible gracias al apoyo log&iacute;stico de la Unidad de Tecnolog&iacute;a Marina, del CSIC, y del buque de investigaci&oacute;n oceanogr&aacute;fica <i>Las Palmas</i> de la Armada. &nbsp;</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&nbsp;</span></span></p> <ul> <li><span style="font-size: smaller;"><span style="font-family: Arial;">A. L&oacute;pez-Bueno, A. Rastrojo, R. Peir&oacute;, M- Arenas y A. Alcam&iacute;. <b>Ecological connectivity shapes quasispecies structure of RNA viruses in an Antartic lake</b>. <i>Molecular Ecology</i>. DOI: 10.1111/mec.13321.</span></span><span style="font-size: small;" /><span style="font-size: smaller;"><span style="font-family: Arial;" /></span></li> </ul> <p>&nbsp;</p> <p><a target="_blank" href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/2f8d4d71-1559-4c22-ab4d-46709ceb24fa/12agosto2015_virusRNA_Antartida.pdf"><strong><span style="font-size: small;"><span style="font-family: Arial;">Nota de prensa</span></span></strong></a><em><span style="font-size: small;"><span style="font-family: Arial;"> (pdf 465K)</span></span></em><span style="font-size: small;"><span style="font-family: Arial;" /></span><em><span style="font-size: small;"><span style="font-family: Arial;" /></span></em></p> <p><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/8940f754-a17d-45a7-8863-49b2f203140b/Toma%2520de%2520muestras%2520(ManuelToro_CSIC).jpg" target="_blank"><strong>Fotograf&iacute;a</strong></a><em> (jpg 2,3M)</em></span></span><span style="font-family: Arial;" /></p> <p>&nbsp;</p> <p>&nbsp;</p></div> 2015-08-23T22:58:58Z La revolución industrial detuvo un proceso de 1.800 años de enfriamiento oceánico ENFRIAMIENTO_OCEANOS_12128997.gcl 2015-08-23T22:58:58Z 2015-08-23T22:58:58Z <div class="description">18/08/2015</div><div class="body"><p><span style="font-size: small;"><span style="font-family: Arial;">Un aumento en la frecuencia y magnitud de las erupciones volc&aacute;nicas pudo ocasionar un enfriamiento paulatino de la temperatura superficial del mar durante 1.800 a&ntilde;os, tendencia que se detuvo con la llegada de la revoluci&oacute;n industrial. Esta es una de las principales conclusiones a las que ha llegado un estudio internacional con participaci&oacute;n del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) y que ha sido publicado en la revista <i>Nature Geoscience</i>. Los resultados del trabajo proporcionan una nueva perspectiva al estudio de las variaciones de temperatura en la superficie del oc&eacute;ano a escala regional y global a lo largo de los siglos antes de la aparici&oacute;n del cambio clim&aacute;tico antropog&eacute;nico, es decir, influenciado por la actividad humana. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;El hecho que detectemos de forma consistente una tendencia al enfriamiento tanto en las observaciones llevadas a cabo en tierra como en el mar sugiere que dicha tendencia en la &eacute;poca pre-industrial era robusta, sobre todo en el &uacute;ltimo milenio. Esta tendencia ha sido revertida por un calentamiento estad&iacute;sticamente significativo en los dos &uacute;ltimos siglos&rdquo;, explica la investigadora del CSIC Bel&eacute;n Martrat, del Instituto de Diagn&oacute;stico Ambiental y Estudios del Agua.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Seg&uacute;n este estudio, las temperaturas m&aacute;s bajas a lo largo de los 1.800 a&ntilde;os de enfriamiento oce&aacute;nico se produjeron sobre todo hacia la &uacute;ltima parte del periodo que en tierra firme se conoce como la Peque&ntilde;a Edad del Hielo, esto es, aproximadamente desde el siglo XVI al XVIII, con consecuencias documentadas hist&oacute;ricamente, por ejemplo, en las sociedades europeas. &ldquo;Sab&iacute;amos que, a corto plazo, las erupciones volc&aacute;nicas tienen un efecto refrigerante sobre la atm&oacute;sfera. Ahora nuestros resultados muestran que, cuando la actividad volc&aacute;nica se produce de manera m&aacute;s frecuente, ese efecto refrigerante se prolonga en el oc&eacute;ano&rdquo;, afirma Helen McGregor, de la Universidad de Wollongong, en Australia.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Los investigadores han llegado a estos resultados al combinar por primera vez 57 estudios previos sobre la evoluci&oacute;n temporal de la temperatura superficial oce&aacute;nica estimada a partir de materiales f&oacute;siles marinos, que han sido extra&iacute;dos de sedimentos acumulados de forma uniforme en los fondos oce&aacute;nicos. Los resultados se compararon posteriormente con datos obtenidos mediante indicadores terrestres, como los anillos de los &aacute;rboles o los testigos de hielo. Para observar las tendencias a largo plazo, la informaci&oacute;n fue agrupada en tramos de 200 a&ntilde;os.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Los modelos clim&aacute;ticos han sido fundamentales para descubrir las causas de ese enfriamiento. Examinamos varios de los factores que pod&iacute;an afectar a la temperatura superficial oce&aacute;nica, como la actividad solar, los cambios en los par&aacute;metros orbitales terrestres, los usos de la tierra, la actividad volc&aacute;nica y los gases de efecto invernadero. De todos ellos, la actividad volc&aacute;nica se revel&oacute; como determinante para reproducir la tendencia que coincid&iacute;a con las observaciones&rdquo;, a&ntilde;ade Martrat. </span></span></p> <p><strong><span style="font-size: small;"><span style="font-family: Arial;">Entender el pasado para mirar hacia el futuro</span></span></strong><span style="font-size: small;" /></p> <p><span style="font-size: small;"><span style="font-family: Arial;">La se&ntilde;al de enfriamiento detectada en los registros marinos muestra el modo en que act&uacute;a el oc&eacute;ano como regulador del clima. En comparaci&oacute;n con la atm&oacute;sfera, el oc&eacute;ano puede absorber grandes cantidades de calor. Como consecuencia, se retrasa sustancialmente el calentamiento del clima de la superficie para despu&eacute;s actuar como emisor de ese calor. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Todav&iacute;a estamos aprendiendo sobre el papel de los oc&eacute;anos como mediadores en las variaciones clim&aacute;ticas. La detecci&oacute;n de los factores que cambiaron las temperaturas del oc&eacute;ano en el pasado nos abre una ventana hacia la comprensi&oacute;n de los cambios clim&aacute;ticos inferidos para los pr&oacute;ximos siglos&rdquo;, afirma Mike Evans, de la Universidad de Maryland (Estados Unidos). </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Los investigadores McGregor y Evans forman parte junto a Martrat del equipo que lidera el grupo de trabajo Ocean2k de <i>PAGES</i> (<i>Past Global Changes</i>), que actualmente cuenta con m&aacute;s de 75 miembros conectados a una red formada por cerca de 600 cient&iacute;ficos. Desde la formaci&oacute;n del grupo en 2011, decidieron recurrir a la comunicaci&oacute;n virtual para realizar su trabajo, como medida para reducir su huella de carbono, lo cual &ldquo;ha sido un reto organizativo, pero tambi&eacute;n una experiencia muy positiva en todos los sentidos&rdquo;, concluye Martrat. El CSIC acoger&aacute; en Barcelona, del 6 al 8 de octubre en CosmoCaixa, la primera reuni&oacute;n presencial del grupo, en la que se profundizar&aacute; en las conclusiones de sus estudios y se planear&aacute; el seguimiento de las l&iacute;neas de investigaci&oacute;n abiertas.</span></span><span style="font-size: small;"><span style="font-family: Arial;">&nbsp;</span></span></p> <ul> <li><span style="font-size: smaller;"><span style="font-family: Arial;">Helen V. McGregor, Michael N. Evans, Hugues Goosse, Guillaume Leduc, Belen Martrat, Jason A. Addison, P. Graham Mortyn, Delia W. Oppo, Marit-Solveig Seidenkrantz, Marie-Alexandrine Sicre, Steven J. Phipps, Kandasamy Selvaraj, Kaustubh Thirumalai, Helena L. Filipsson and Vasile Ersek. <b>Robust global ocean cooling trend for the pre-industrial Common Era</b>. <i>Nature Geoscience</i>. DOI: 10.1038/NGEO2510</span></span></li> </ul> <p><span style="font-size: small;"><a target="_blank" href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/a1023eb8-2dc8-41bc-96d7-063badfeeac5/18agosto2015temperatura_oceanos.pdf"><span style="font-family: Arial;"><strong>Nota de prensa</strong></span></a><span style="font-family: Arial;"> (<em>151 kb</em>)</span></span><span style="font-size: smaller;"><span style="font-family: Arial;" /></span>&nbsp;</p></div> 2015-08-23T22:58:58Z Los astrocitos ayudan a coordinar la actividad neuronal ASTROCITOS_CAJAL_12126937.gcl 2015-08-23T22:58:58Z 2015-08-23T22:58:58Z <div class="description">14/08/2015</div><div class="body"><p><span style="font-size: small;"><span style="font-family: Arial;">Los astrocitos, uno de los principales tipos de c&eacute;lulas cerebrales junto con las neuronas, participan activamente en la coordinaci&oacute;n de la actividad cerebral. Esta es una de las principales conclusiones a las que ha llegado un estudio liderado por el Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) y que ha sido publicado en el &uacute;ltimo n&uacute;mero de la revista <i>Science</i>. Seg&uacute;n los resultados del trabajo, los astrocitos podr&iacute;an desempe&ntilde;ar un papel importante en el desarrollo de futuras terapias contra ciertas patolog&iacute;as cerebrales, como las enfermedades de Parkinson y Huntington.</span></span> <table width="450" cellspacing="1" cellpadding="1" border="0" align="right"> <tbody> <tr> <td><img width="450" height="262" src="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/64f65be7-d36f-4201-be87-083f451367e7/foto_nota.jpg" alt="" /><br /> <p><span style="font-size: smaller;"><span style="font-family: Arial;">Imagen de microscop&iacute;a confocal donde se muestran neuronas (verde) y astrocitos (rojo). /(CSIC)</span></span></p> </td> </tr> </tbody> </table> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Sab&iacute;amos que los astrocitos pueden modular la actividad de las sinapsis, que son los lugares en los que se transfiere la informaci&oacute;n de una neurona a otra, pero desconoc&iacute;amos si todos ellos actuaban de una misma forma o, al igual que ocurre con las neuronas, exist&iacute;a una especializaci&oacute;n funcional que les permitiera actuar selectivamente sobre sinapsis concretas&rdquo;, explica Ricardo Mart&iacute;n, investigador del CSIC en el Instituto Cajal.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Para resolver esa inc&oacute;gnita, los investigadores estudiaron las propiedades de la comunicaci&oacute;n entre astrocitos y neuronas en una regi&oacute;n cerebral conocida como estriado, involucrada en la planificaci&oacute;n y ejecuci&oacute;n de movimientos, as&iacute; como en la adquisici&oacute;n de h&aacute;bitos de comportamiento. &ldquo;Nuestros resultados muestran que existen dos subpoblaciones de astrocitos que responden de manera espec&iacute;fica a la actividad de las neuronas que componen los dos principales circuitos del estriado y que, a su vez, cada subpoblaci&oacute;n de astrocitos modula s&oacute;lo aquellas neuronas del mismo circuito. Para modular estas sinapsis los astrocitos liberan glutamato, que regula la eficacia de la transmisi&oacute;n de la se&ntilde;al que una neurona env&iacute;a a otra&rdquo;, a&ntilde;ade la investigadora del CSIC Raquel Bajo, del Instituto Cajal. </span></span></p> <h3><span style="font-size: small;"><span style="font-family: Arial;">Diana terap&eacute;utica contra el p&aacute;rkinson</span></span></h3> <p><span style="font-size: small;"><span style="font-family: Arial;">Este trabajo aporta, adem&aacute;s, nuevos datos sobre el comportamiento de los mecanismos celulares asociados a ciertas patolog&iacute;as cerebrales, como las enfermedades de Parkinson y Huntington, en las que se sabe que influyen los desequilibrios en la actividad de estos dos circuitos neuronales del estriado. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Las disfunciones de la se&ntilde;alizaci&oacute;n entre astrocitos y neuronas podr&iacute;an tener un papel importante en estas enfermedades. Por tanto, los astrocitos podr&iacute;an servir de nuevas dianas celulares para el desarrollo de estrategias terap&eacute;uticas, tanto para P&aacute;rkinson y Huntington, como para otros trastornos del comportamiento en los que la funci&oacute;n del estriado est&eacute; alterada, como ocurre en el trastorno obsesivo-compulsivo&rdquo;, comenta Mart&iacute;n. </span></span></p> <h3><span style="font-size: small;"><span style="font-family: Arial;">Nuevo paradigma de la fisiolog&iacute;a cerebral</span></span></h3> <p><span style="font-size: small;"><span style="font-family: Arial;">Frente al concepto cl&aacute;sico de que la funci&oacute;n cerebral es el resultado &uacute;nicamente de la actividad de las neuronas, este estudio propone que en realidad se trata de una actividad coordinada entre astrocitos y neuronas. &ldquo;Estos resultados ponen de manifiesto que los astrocitos son c&eacute;lulas funcionalmente diferenciadas que modulan espec&iacute;ficamente la actividad de circuitos neuronales concretos, lo que los convierte en un elemento clave en lo que denominamos como &lsquo;redes astro-neuronales&rsquo;. Es, por tanto, un cambio en el paradigma de la fisiolog&iacute;a y patolog&iacute;a cerebral&rdquo;, concluye Bajo.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&nbsp;</span></span></p> <ul> <li><span style="font-size: smaller;"><span style="font-family: Arial;">R. Mart&iacute;n, R. Bajo-Gra&ntilde;eras, R. Moratalla, G. Perea, A. Araque. Circuit-specific signaling in astrocyte-neuron networks in basal ganglia pathways. <i>Science</i>. DOI: 10.1126/science.aaa7945</span></span><span style="font-size: small;" /></li> </ul> <p><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/c3ce127f-f00c-48e9-aded-1c829fd0ddd2/14agosto2015astrocitos_science.pdf" target="_blank" title="Los astrocitos ayudan a coordinar la actividad neuronal"><strong><span style="font-size: small;"><span style="font-family: Arial;">Nota de prensa</span></span></strong></a><span style="font-size: small;"><span style="font-family: Arial;"> <em>(pdf 252K)</em></span></span></p> <p><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/35552f8d-d8bc-49e6-9a9c-b75c3ad25563/Astrocitos%2520y%2520neuronas.jpg" target="_blank" title="Astrocitos y neuronas"><strong><span style="font-size: small;"><span style="font-family: Arial;">Imagen</span></span></strong></a><span style="font-size: small;"><span style="font-family: Arial;"> <em>(jpg 800K)</em></span></span></p> </p> <p>&nbsp;</p></div> 2015-08-23T22:58:58Z Hallado un nuevo tipo de fármaco con efecto antitumoral contra el cáncer de colon y el melanoma CANCER_CELL_12122377.gcl 2015-08-23T22:58:57Z 2015-08-23T22:58:57Z <div class="description">11/08/2015</div><div class="body"><p><span style="font-size: small;"><span style="font-family: Arial;">Un equipo internacional dirigido por investigadores del Consejo Superior de Investigaciones Cient&iacute;ficas (CSIC) ha descubierto un nuevo tipo de f&aacute;rmaco con un potente efecto antitumoral en modelos animales de c&aacute;ncer colorrectal y melanoma. Varias compa&ntilde;&iacute;as se han interesado en el compuesto para estudiar sus posibles aplicaciones como terapia antitumoral en humanos. Los resultados del estudio se publican en la revista <i>Cancer Cell</i>.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Los investigadores han identificado una mol&eacute;cula, DEL-22379, que logra causar la muerte de las c&eacute;lulas tumorales, seg&uacute;n explica el director del estudio, Piero Crespo, investigador del CSIC en el Instituto de Biomedicina y Biotecnolog&iacute;a y de Cantabria. &ldquo;Hasta la fecha, se ha comprobado la eficacia de DEL-22379 en modelos animales de c&aacute;ncer de colon y de melanoma, pero tambi&eacute;n se ha empezado a ensayar para c&aacute;ncer de tiroides, pulm&oacute;n y p&aacute;ncreas&rdquo;, a&ntilde;ade.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">En el desarrollo de los c&aacute;nceres tiene una importancia crucial la ruta bioqu&iacute;mica RAS-ERK: &ldquo;Aproximadamente el 50% de los tumores humanos portan mutaciones en alg&uacute;n componente de la ruta bioqu&iacute;mica RAS-ERK, a trav&eacute;s de la cual las c&eacute;lulas regulan su proliferaci&oacute;n&rdquo;, explica Crespo. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Esta ruta, constituida por cuatro prote&iacute;nas, en condiciones normales se pone en funcionamiento en respuesta a se&ntilde;ales extracelulares que dictan a las c&eacute;lulas cu&aacute;ndo y cu&aacute;nto deben proliferar. Las cuatro prote&iacute;nas se activan una a otra, secuencial y sucesivamente, acoplando una cadena de transmisi&oacute;n, a trav&eacute;s de la cual se ponen en funcionamiento los mecanismos necesarios para la proliferaci&oacute;n celular&rdquo;, a&ntilde;ade. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;En las c&eacute;lulas tumorales, las mutaciones en alguno de los componentes de la ruta RAS-ERK hacen que, en ausencia de se&ntilde;ales extracelulares, dicha cadena de transmisi&oacute;n est&eacute; activada de forma aberrante, constantemente, por lo que las c&eacute;lulas proliferan descontroladamente&rdquo;, detalla el investigador.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Las compa&ntilde;&iacute;as farmac&eacute;uticas llevan 25 a&ntilde;os buscando mol&eacute;culas que puedan inhibir la actividad de alguno de los componentes de dicha ruta para atajar la proliferaci&oacute;n de c&eacute;lulas tumorales. &ldquo;Fruto de esa investigaci&oacute;n son una serie de f&aacute;rmacos utilizados actualmente en el tratamiento de varios tipos de tumores, con efectos menos exitosos de los que cab&iacute;a esperar&rdquo;, se&ntilde;ala el investigador.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">La estrategia dise&ntilde;ada por el equipo de Crespo es muy diferente: no busca inhibir la actividad de los componentes sino hallar un compuesto que rompa el flujo de se&ntilde;ales por la ruta RAS-ERK, desacoplando interacciones moleculares en alg&uacute;n punto clave de la cadena de transmisi&oacute;n. Esto es lo que logra la mol&eacute;cula DEL-22379, que evita la asociaci&oacute;n (dimerizaci&oacute;n) entre dos prote&iacute;nas ERK.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">En estos momentos, el CSIC trabaja en la patente de derivados de DEL-22379. Diversas compa&ntilde;&iacute;as se han interesado en el compuesto para determinar si dicho compuesto, o sus derivados mejorados, pueden ser utilizados como terapia antitumoral en humanos. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">Sin embargo, Crespo es cauto: &ldquo;el 80% de los compuestos antitumorales descubiertos fracasa en el paso de animales de laboratorio a humanos&rdquo;. &ldquo;No obstante, aunque as&iacute; fuese, la importancia de este hallazgo reside en el concepto, mucho m&aacute;s que en el compuesto en s&iacute;&rdquo;, explica. </span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&ldquo;Hay centenares de interacciones prote&iacute;na-prote&iacute;na con potencial de ser utilizadas como dianas antitumorales. Esperamos que nuestro trabajo sirva de inspiraci&oacute;n para que otros cient&iacute;ficos se interesen en otras interacciones de este tipo en la b&uacute;squeda de nuevos abordajes para combatir el c&aacute;ncer&rdquo;. &ldquo;Hemos abierto un nuevo camino&rdquo;, concluye.</span></span></p> <p><span style="font-size: small;"><span style="font-family: Arial;">&nbsp;</span></span></p> <ul> <li><span style="font-size: smaller;"><span style="font-family: Arial;">Ana Herrero, Ad&aacute;n Pinto, Paula Col&oacute;n-Bolea, H&eacute;ctor G. Palmer, Adam Hurlstone, Piero Crespo. <b>Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes</b>. <i>Cancer Cell</i>. Doi: 10.1016/j.ccell.2015.07.001</span></span><span style="font-size: small;" /></li> </ul> <p><strong><span style="font-size: small;"><span style="font-family: Arial;"><a href="http://documenta.wi.csic.es/alfresco/downloadpublic/direct/workspace/SpacesStore/b51db840-ea8d-4eeb-ac19-d0ee85fe1c84/10agosto2015%2520f%25c3%25a1rmaco%2520antitumoral.pdf" target="_blank" title="Hallado un nuevo tipo de f&aacute;rmaco con efecto antitumoral contra el c&aacute;ncer de colon y el melanoma" type="PDF">Nota de prensa</a> </span></span></strong><em><strong><span style="font-size: small;"><span style="font-family: Arial;" /></span></strong><span style="font-size: small;"><span style="font-family: Arial;">(pdf K)</span></span></em><span style="font-size: small;"><span style="font-family: Arial;" /></span></p> <p>&nbsp;</p> <p>&nbsp;</p></div> 2015-08-23T22:58:57Z